Synthesis, Reprecipitation Method and Pharmacological Potency of Free Porphyrin Based Nanoparticles

نویسنده

  • RASHA E. EL-MEKAWY
چکیده

We have designed and synthesized a new symmetrical porphyrins 3a-d and their nanoparticles based on extended π-conjugation concept. The new sensitizers were fully characterized by CHN analysis, UV-Vis., H-NMR, TEM and Mass spectroscopy. The new sensitizers and their nanoparticles were evaluated as antitumor activity against HepG2, WI-38, VERO and MCF-7 cell lines. It was found that porphyrin nanoparticles have the most potent activity.

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تاریخ انتشار 2014